Active Pharmaceutical Ingredient(API) Screening Solution - Xinxiang Gaofu Machinery Co., Ltd
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Active Pharmaceutical Ingredient(API) Screening Solution

Solution introduction

Active Pharmaceutical Ingredient, intermediate synthesis of materials in different particle size, uneven particle size was devalued or even rejected. Powder because of excessive levels of plant fiber so that the value can not be improved, pills size is different, adhesions, API specifications is various, nearly a thousand species, Active Pharmaceutical Ingredient has: material sticky, adsorption, sieve blocking, material surface shape, bulk density demanding strictly, can not be damaged, such as capsule pellets raw materials.

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Screening needs

  • Screening purpose: impurity removal and classification
  • Equipment used: rotary vibrating screen, ultrasonic vibrating sieve
  • Screening mesh: 24-100 mesh
  • Screening capacity: 50-700kg/h

Process flow

Raw material extraction - Filtration - Crystallization - Separation - Drying - Screening - Inner packaging - Outer packaging

Introduction

APIs are approved by the chemical synthesis, plant extracts or biotechnology prepared for use as a medicinal powder, crystal, extract, etc., but the patient can not take directly, it needs further processing.

This product is white or white flaky crystal or crystalline powder, odorless, taste astringent. This product is slightly soluble in water, very slightly soluble in ethanol, almost insoluble in chloroform refers to the raw materials used to produce various types of drugs, is the active ingredient in the preparation, by chemical synthesis, plant extracts or biotechnology prepared Used as a medicinal powder, crystal, extract, etc., but the patient can not directly take the material. According to its source of raw materials divided into chemical synthetic drugs and natural chemical drugs two categories.

Chemical synthetic medicine can be divided into inorganic synthetic medicine and organic synthetic medicine. Inorganic synthetic medicine is inorganic compounds (very individual elements), such as for the treatment of stomach and duodenal ulcer aluminum hydroxide, magnesium trisilicate; organic synthetic drugs mainly by the basic organic chemical raw materials, after a series of organic Chemical reaction and prepared drugs (such as aspirin, chloramphenicol, caffeine, etc.).

Natural chemical medicine: Biochemical drugs can also be divided into two categories of chemical and phytochemicals. Antibiotics are generally made by microbial fermentation, which belongs to the category of biochemistry. In recent years, a variety of semi-synthetic antibiotics, it is a combination of biosynthesis and chemical products. Among the APIs, the varieties of organic synthetic medicine, the largest proportion of output and output value, are the main pillars of the chemical and pharmaceutical industry. The quality of the medicine substance determines the quality of the preparation, so its quality standards are very strict. The countries in the world have formulated strict national pharmacopoeia standards and quality control methods for their widely used APIs.

API use

Active Pharmaceutical Ingredient, intermediate synthesis of materials in different particle size, uneven particle size was devalued or even rejected. Powder because of excessive levels of plant fiber so that the value can not be improved, pills size is different, adhesions, API specifications is various, nearly a thousand species, Active Pharmaceutical Ingredient has: material sticky, adsorption, sieve blocking, material surface shape, bulk density demanding strictly, can not be damaged, such as capsule pellets raw materials.

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Before rectification

The dust removal fan is installed directly on the top. There is a resin composite-coated filter element to control flying materials. Qualified materials are intercepted and placed in the security screen. The dust is removed by the fan to improve the operating environment and ensure the health of workers.
Compactly installed under the feeding platform, the screen machine does not require any tools to operate, the noise is less than 70 decibels, it is easy to clean, there are no dead corners, and the maintenance rate is low. Its main function is to intercept particles and foreign matter that are larger than the screen aperture. Energy consumption: Ordinary diameter 1000 machine, motor power is 1.1KW; this security screen motor power is 0.55KW, industrial electricity consumption is 1 yuan/degree, saving 0.45 yuan per hour * 8 hours / day = 3.6 yuan.
Magnet separator: installed under the screen, used to absorb iron filings smaller than the screen aperture.

After rectification

1、Workers’ environmental work subsidy: For environmental work in dusty areas, the monthly subsidy for special work types is 500 yuan per person;
2、The inspection and certification by the superior environmental department is qualified, and the rectification is carried out as a low-level, which takes 3 days to complete. The entire line is stopped for production losses, and other expenses are not included. The worker wages are calculated based on 5 people, 100 people/day, totaling 1,500 yuan;
3、Dust flying and normal loss during operation: calculated as 2 kg per shift, priced at 1.5 yuan per kilogram, totaling 3 yuan/day.

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